Calendar

««Sep 2008»»
SMTWTFS
 
1
2
3
4
5
6
7
8910111213
14151617181920
21222324252627
282930
  More

Search Box

 

Mailing List

RSS Feeds








Add to Jamespot
Widgetize!

Translate



Link to Ai profile Link to Anxiety Community Link to Wellsphere

Health Wisdom

HealthCentral Top Site Award

IBS Tales Hope Award

Disclaimer

All content within Anxiety Insights is provided for general information only, and should not be treated as a substitute for the medical advice of your doctor or other health care professional.

Anxiety Insights is not responsible or liable for any diagnosis made by a reader based on the content of this website.

Anxiety Insights is not liable for the contents of any external internet sites listed, nor does it endorse any commercial product or service mentioned or advised on any of the sites.

Always consult your doctor if you are in any way concerned about your health.

recommended links

Depression is Real's Down & Up Show
      Weekly audio-casts from the
      Depression Is Real Coalition

we support

Kiva.org - micro loans that change lives

Moving a Nation to Care : Post Traumatic Stress Disorder and America's Returning Troops, by Ilona Meagher

No Longer Lonely.com

"just don't smoke"


"Don't smoke, whatever you do, just don't smoke."
                        Yul Brynner

Hit Counter

Total: 1,692,661
since: 14 May 2006

Poly antidepressant treatment and diabetes risk

posted Wednesday, 26 March 2008

antidepressants diabetes

While analyzing data from Saskatchewan health databases, Lauren Brown, a researcher with the University of Alberta School of Public Health, found people with a history of depression had a 30 per cent increased risk of type 2 Diabetes.

Brown then studied the medical history of 2,400 people who were diagnosed with depression and were taking antidepressants to determine whether there was a clear correlation between that disease and type 2 Diabetes.

Brown divided the group into four categories: those who took antidepressants that were considered older therapies, patients who were using newer treatments, those using a combination of both an old and new treatments and people who were switching medications.

What she found was the risk of diabetes almost doubled for the patients who were using two types of therapies at the same time, tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs). Brown says people are usually prescribed multiple medications "if they have severe depression or if they are having a problem finding the right therapy."

Brown believes these results, and results of previous studies demonstrating an increased risk of type 2 diabetes in people with depression, emphasize the need for regular screening for type 2 diabetes in people with depression, particularly those taking more than one antidepressant. She also encourages diabetes and depression organizations to educate their members about this link.


Brown LC, Majumdar SR, Johnson JA. Type of antidepressant therapy and risk of type 2 diabetes in people with depression. Diabetes Res Clin Pract. 2008 Jan;79(1):61-7.   [Abstract]
Comment:  
While this research found a link between diabetes and the concurrent use of TCA with SSRI class antidepressants, it is unclear whether the increased risk is from the antidepressants, or that poly antidepressant use is an indication that the patients had more severe depression which increased diabetes susceptibility. A number of previous studies have shown that anxiety and depressive disorders are themselves significant risk factors for type II diabetes.

If you are taking both a TCA and SSRI antidepressant and are in a high diabetes risk group consult the prescribing physician about changing the treatment regime.

Caution: Antidepressants should never be quit "cold-turkey" but weaned off slowly over a period of weeks or months. Ask your doctor for a weaning schedule if you intend to discontinue treatment.

tags:      

links: digg this    del.icio.us    technorati    reddit