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Comorbid PTSD affects depression and pain severity

posted Tuesday, 22 July 2008

PTSD pain depression

Patients with accident or trauma related chronic pain often have post-traumatic stress disorder (PTSD) and depression. What isn't clearly, however, is how PTSD relates to mood disorders and pain severity in chronic pain patients.

To find out University of Michigan researchers examined the contribution of PTSD to the pain experience, functional disability and frequency of depressive symptoms. They studied 241 patients referred to the university hospital's pain rehabilitation program who reported their pain began after a traumatic injury. The subjects completed the McGill Pain Questionnaire and were administered the Pain Disability Index and the Post-traumatic Chronic Pain Test.

Results showed PTSD and depression are significantly correlated and both disorders are associated with perceived disability attributed to chronic pain. Therefore, in cases of disabling accident-related chronic pain with comorbid depression, symptoms of PTSD may be critical to understanding both disorders.

The authors concluded that increased attention to treating PTSD as a primary focus in the rehabilitation of patients with chronic pain and comorbid depression is important when prior treatment efforts for pain and depression have not been successful.


Roth RS, Geisser ME, Bates RB. The Relation of Post-traumatic Stress Symptoms to Depression and Pain in Patients with Accident-related Chronic Pain J Pain. 2008 Jul;9(7):588-96.   [Abstract]

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